According to the new market research report “Phosphodiesterase Type 5 (PDE5) Inhibitor - Global Market Share and Ranking, Overall Sales and Demand Forecast 2024-2030”, published by QYResearch, the global Phosphodiesterase Type 5 (PDE5) Inhibitor market size is projected to reach USD 2728.6 million by 2029, at a CAGR of 3.3% during the forecast period.
Phosphodiesterase type 5 (PDE5) inhibitor is a class of medication that specifically targets and blocks the enzyme phosphodiesterase type 5. This enzyme is primarily found in the smooth muscle cells of the blood vessels, including those in the penis and lungs. By inhibiting PDE5, these medications promote the accumulation of cyclic guanosine monophosphate (cGMP), a chemical responsible for relaxing the smooth muscles and increasing blood flow in these areas. In the context of erectile dysfunction (ED), PDE5 inhibitors help improve blood flow to the penis, facilitating and maintaining erections. They are also used in the treatment of pulmonary arterial hypertension (PAH) to reduce blood vessel constriction and lower blood pressure in the lungs.
- Global Phosphodiesterase Type 5 (PDE5) Inhibitor MarketSize(US$ Million), 2018-2029
Source: QYResearch, "Phosphodiesterase Type 5 (PDE5) Inhibitor - Global Market Share and Ranking, Overall Sales and Demand Forecast 2024-2030”
- Global Phosphodiesterase Type 5 (PDE5) Inhibitor Top11Players Ranking and Market Share (Ranking is based on the revenue of 2022, continually updated)
Source: QYResearch, "Phosphodiesterase Type 5 (PDE5) Inhibitor - Global Market Share and Ranking, Overall Sales and Demand Forecast 2024-2030”
The global key manufacturers of Phosphodiesterase Type 5 (PDE5) Inhibitor include Eli Lilly, Pfizer, Bayer, BaiYunShan General Factory, Teva Pharma, SK Chemicals, Seoul Pharma, Jiangsu Yabang, VIVUS, Fujian Cosunter, etc. In 2022, the global top five players had a share approximately 81.0% in terms of revenue.
Market Drivers:
Increasing incidence of erectile dysfunction (ED): ED is a common sexual health disorder affecting a significant number of men globally.
Growing awareness and acceptance: There has been an increased awareness and acceptance of ED as a medical condition.
Aging population: The global population is aging, with a larger proportion of older individuals. Since ED becomes more prevalent with age, the aging population creates a larger customer base for PDE5 inhibitors.
Restraint:
Adverse Effects: PDE5 inhibitors may cause side effects such as headache, flushing, nasal congestion, vision changes, etc.
Alternative treatment options: Besides PDE5 inhibitors, there are alternative treatment options available for erectile dysfunction (ED).
Market Trend:
Increasing incidence of ED: The prevalence of ED is expected to rise due to factors such as an aging population, lifestyle changes, and the growing awareness and diagnosis of the condition. This increased demand for treatment options is going to impact the PDE5 inhibitor market positively.
Growing market competition: With the expiry of patents for some PDE5 inhibitors, the market has seen the entry of generic versions of drugs like Viagra (sildenafil) and Cialis (tadalafil). This has led to increased competition among manufacturers, potentially resulting in lower prices for consumers.
Research on alternative treatment approaches: While PDE5 inhibitors have been a primary treatment for ED, ongoing research is focused on identifying and developing alternative therapies. This includes exploring new drug candidates or investigating non-pharmaceutical interventions such as shockwave therapy, stem cell therapy, and lifestyle modifications.
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