β-Lactams are the most widely used class of antibiotics. Since the discovery of benzylpenicillin in the 1920s, thousands of new penicillin derivatives and related β-lactam classes of cephalosporins, cephamycins, monobactams, and carbapenems have been discovered. Each new class of b-lactam has been developed either to increase the spectrum of activity to include additional bacterial species or to address specific resistance mechanisms that have arisen in the targeted bacterial population. Resistance to β-lactams is primarily because of bacterially produced β-lactamase enzymes that hydrolyze the β-lactam ring, thereby inactivating the drug. The newest effort to circumvent resistance is the development of novel broad-spectrum β-lactamase inhibitors that work against many problematic β-lactamases, including cephalosporinases and serine-based carbapenemases, which severely limit therapeutic options.
According to the new market research report “Beta-lactam and Beta-lactamase Inhibitors - Global Market Share and Ranking, Overall Sales and Demand Forecast 2024-2030”, published by QYResearch, the global Beta-lactam and Beta-lactamase Inhibitors market size is projected to reach USD 32.39 billion by 2029, at a CAGR of 2.5% during the forecast period.
- Global Beta-lactam and Beta-lactamase Inhibitors MarketSize(US$ Million), 2018-2029
Source: QYResearch, "Beta-lactam and Beta-lactamase Inhibitors - Global Market Share and Ranking, Overall Sales and Demand Forecast 2024-2030”
- Global Beta-lactam and Beta-lactamase Inhibitors Top17Players Ranking and Market Share (Ranking is based on the revenue of 2022, continually updated)
Source: QYResearch, "Beta-lactam and Beta-lactamase Inhibitors - Global Market Share and Ranking, Overall Sales and Demand Forecast 2024-2030”
The global key manufacturers of Beta-lactam and Beta-lactamase Inhibitors include Pfizer, USantibiotics, Novartis (Sandoz), Antibiotice, TEVA, Merck & Co., Fresenius Kabi, AbbVie (Allergan), Sumitomo Dainippon, ACS Dobfar, etc. In 2021, the global top 10 players had a share approximately 26.0% in terms of revenue.
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